"The 4-Hour Workweek" by Timothy Ferriss is close to being a self-help book but with a twist. It deals with what Ferriss refers to as "lifestyle design" and repudiates the traditional life plan in which people work long hours and take few vacations in order to save money and relax after retirement. I wouldn't call this self help, I would rather call it a blueprint of what you can do with your time, you don't have to do anything but if something in the book can be applied to your situation, then use it. I was a bit skeptical at first but when you start to understand what Timothy is trying to say with each chapter, it is a nice book to read.
I wouldn't say that every chapter is for everyone, however, the mentality can be used in everyday life. The book is essentially a list of problems and different ways you can overcome them by using, internet, contacts and so on. This book can change your life in the long run and could potentially help you make big positive change in a short time frame. The smart thing about every book you read is that you, as a reader, can decide what to focus on, the same rules apply for this book and if you use that correctly and look for things that could simplify your life, then this can be a great book for you.